METABOLISM OF GLUCURONIC ACID IN FATIGUE DUE TO PHYSICAL EXERCISE

Metabolism of glucuronic acid in fatigue due to physical exercise.

田村 俊吉*・富沢 摂 夫 ・堤 璋二*・勝 呂 信雄 ・木津 弘司 ・伊藤 博夫 ・中井 一仁 ・北 進一 ・増田 紀男 Present address : * Department of Pharmacology , Tokyo Dental College, Chiyoda-ku, Tokyo. Concerning the cause of fatigue, there have been many assumptions on the basis of energy accumulation of substances inducing fatigue. There have been a lot of studies (1, 2) on piling up of the so-called fatigue substances. In the book edited by...

Investigation of glucuronic acid metabolism in human subjects.

Ischemic colitis due to vigorous physical exercise.

Physical exercise has been related with both beneficial effects on the gastrointestinal tract as with adverse effects on the latter. Gastrointestinal bleeding is one of these. In general, gastrointestinal bleeding is transient and mild. However, some cases caused by intestinal ischemia can sometimes be more serious due to the amount of bleeding and the presence of mucosal lesions. We present th...

Studies on the glucuronic acid pathway of glucose metabolism.

Studies on the formation of n-ascorbic acid and n-xylulose in animals have led to the postulation (1, 2) of a cyclic pathway of glucose metabolism by way of n-glucuronic acid, n-gulonic acid, n-xylulose, n-xylulose, and the pentose phosphate sequence (Fig. 1). Preliminary experiments from this laboratory (3) designed to test this hypothesis have shown that labeled Lgulonolactone is readily conv...

Microanalysis of Glucuronide Glucuronic Acid as Applied to /3-glucuronidase and Glucuronic Acid Studies*

In recent years, interest in the metabolism of glucuronic acid has grown. Contributions have ranged from studies of its biosynthesis and conjugation in surviving tissues and exper,imental animals to its utilization in man (l-lo). In all spheres, especially the latter, progress has been hampered by the lack of an analytical method by which glucuronides could be differentiated from free glucuroni...